Q. There’s poison ivy, and there’s poison ivy! My husband gets a barely noticeable, itchy rash that doesn’t impact his daily life in any measurable way. When I get poison ivy, I swell up like a balloon. The blisters are the size of half golf balls, and when they finally start draining, it takes days before the oozing stops. Twice in my life I spent over a week in bed prior to finally going to the doctor for help. I was only able to get up to use the bathroom, which was agony. For me, a typical course of poison ivy lasts more than two weeks. Prednisone is a lifesaver in my case.