CANTON (AP) -- Andre Williams ran up some big numbers at Boston College. The fourth-round draft pick is showing glimpses that can do it for the New York Giants, too.
Williams had seven carries for 48 yards and scored on a 3-yard run in a 17-13 victory over the Buffalo Bills on Sunday night in the preseason-opening Hall of Fame Game.
"It gives me confidence. I feel like I'm supposed to be here," said Williams, who led the nation with 2,177 yards rushing last season. "I'm part of the team now."
And a more important part with David Wilson sidelined after sustaining his second neck injury in less than a year.
Filling the No. 2 spot behind newly acquired starter Rashad Jennings, the Heisman Trophy finalist helped provide the Giants' re-tooled backfield a 1-2 punch.
Williams' score, which came after a 21-yard scamper off left tackle, put the Giants up 7-3 late in the first quarter.
Rookie receiver Corey Washington scored the go-ahead touchdown on a 73-yard pass up the right sideline from backup Ryan Nassib with 13:18 remaining. Washington reached back to catch the partly under-thrown pass, then stepped around flat-footed defender Kamaal McIlwain.
Starter Eli Manning played three series, and finished 6 of 7 for 43 yards, but lost a fumble.
For Buffalo, starting quarterback EJ Manuel had several lapses during two series. He completed just 2 of 7 attempts for 19 yards, and nearly had a pass intercepted by linebacker Jacquian Williams inside the New York 10. Manuel never looked off his intended target Sammy Watkins and was fortunate to have Williams bat the ball down.
Bills backup Jeff Tuel hit Robert Woods for a 2-yard touchdown pass on fourth-and-goal to put Buffalo ahead 10-7 early in the second quarter. Tuel finished 12 of 17 for 74 yards and an interception.
The NFL unveiled a few new wrinkles that will run through the first two weeks of the preseason.
New York's Josh Brown hit two and Dan Carpenter hit his extra-point attempt, all of which were snapped from the 15-yard line rather than the 2.