COLLEGE STATION, Texas (AP) -- AJ McCarron and Alabama was not about to let Johnny Manziel and Texas A&M get another signature win.
McCarron nearly matched the Heisman Trophy winner with four touchdown passes, and Vinnie Sunseri returned an interception 73 yards for a score -- sidestepping Johnny Football on the way to the end zone, too -- as No. 1 Alabama paid back No. 6 Texas A&M with a 49-42 victory Saturday.
Alabama (2-0, 1-0 Southeastern Conference) spotted the Aggies (2-1, 0-1) a 14-0 lead, shades of last season when A&M jumped out to a 20-0 lead in Tuscaloosa on the way to victory that all but won the Heisman for Manziel.
McCarron and the Tide didn't take as long to respond this time, ripping off the next 35 points. McCarron tossed three touchdowns in the first half to put Alabama up 28-14. Sunseri's pick-6 made it 35-14 less than three minutes into the third.
Manziel was his spectacular self, throwing for a career-best 464 yards and five TDs. But a first-half interception in the end zone swung the game the Tide's way, and his third-quarter pick and whiff on the tackle put the Aggies in a deep hole.
Alabama's best defense was its offense. The Tide gained 568 yards and kept Manziel on the bench with a couple of long drives.
The rematch was hyped for months, heightened by offseason drama over Manziel that culminated with the sophomore getting suspended for half the opening game after an NCAA investigation into whether he was paid for signing autographs.
Bama-A&M lived up to the advanced billing. But this SEC heavyweight matchup was no 9-6 Game of the Century. The offenses were all but unstoppable.
A&M's defense was leaky in its first two games against far weaker opponents. Against Alabama, even with the return of four key players from various suspensions, it put up little resistance.
And while the Tide's offense wore out the Aggies, its defense struck a big blow.
Manziel threw deep down the middle to Malcome Kennedy, but Jarrick Williams had tight coverage for Alabama and tipped the pass into the air. Sunseri came down with it and was off in the other direction, stutter-stepping as Manziel slid on by while trying for a one-arm takedown. The safety broke another tackle on the way into the end zone and Alabama was up 35-14.
Manziel walked slowly across the field to the A&M sideline, taking a couple of glances toward the end zone and Alabama's celebration.
A crowd of 87,596 that was booming like a jet engine earlier fell silent. They were hoping to see the Aggies get their third victory against a No. 1 team, and second straight against Alabama.
Alabama was poised to go up three touchdowns in the fourth quarter when Texas A&M's defense slammed into T.J. Yeldon a couple of yards from the goal line, causing a fumble the Aggies recovered at the 5.
Two plays later, Manziel found Mike Evans deep. The big receiver broke away from a tackler and went 95 yards for a score that made it 42-35 with 8:04 left. Manziel sprinted out of his end zone toward the other to celebrate. The crowd was alive again.
Evans finished with 279 yards on seven catches.
In need of a time-consuming drive, leaned on Yeldon and McCarron. On third-and-goal from the 5, McCarron faked the hand off, rolled right and flipped to Jalston Fowler for the touchdown to make it 49-35 with 2:28 left.
Manziel threw one more TD with 15 seconds left, but Alabama grabbed the onside kick and that was that.
No. 2 OREGON 59, TENNESSEE 14
EUGENE, Ore. -- Marcus Mariota threw for a career-high 456 yards and four touchdowns for Oregon. Freshman Johnny Mundt, who replaced ailing tight end Colt Lyerla, had five catches for 121 yards and two TDs for the Ducks (3-0). Josh Huff added six catches for 125 yards and a score.
Mariota, who completed 23 of 33 passes, was the first Oregon quarterback to throw for more than 400 yards in a game since Kellen Clemens in 2005. The sophomore quarterback's yardage ties for the third-most in a game in school history.
Tennessee (2-1) took an early lead, but it was fleeting and the Ducks led 38-7 at halftime.
No. 5 STANFORD 34, ARMY 20
WEST POINT, N.Y. -- Kevin Hogan threw for three touchdowns and Tyler Gaffney had two touchdowns and 132 yards rushing for Stanford.
The Cardinal (2-0) entered the game as 30-point favorites but had their hands full from the opening kickoff, falling behind 6-0 to the much smaller Black Knights (1-2).
Hogan's 23-yard touchdown pass to Gaffney after an Army turnover gave Stanford a 27-13 lead late in the third quarter and the Cardinal averted an embarrassing moment. Army has not defeated a ranked team since a 17-14 win over No. 15 Air Force on Nov. 4, 1972.
No. 7 LOUISVILLE 27, KENTUCKY 13
LEXINGTON, Ky. -- Senorise Perry ran for 100 yards and two touchdowns and Teddy Bridgewater overcame a shaky start to pass for 250 yards for Louisville, which scored on four consecutive drives to pull away from its instate rival.
The Cardinals (3-0) forced three turnovers, including two in their territory to preserve the win.
Bridgewater connected with DeVante Parker for a 13-yard touchdown just before halftime and Perry followed with second-half TD runs of 1 and 36 yards sandwiched around John Wallace's 21-yard field goal.
No. 10 FLORIDA ST. 62, NEVADA 7
TALLAHASSEE, Fla. -- Jameis Winston accounted for three touchdowns and Florida State's four tailbacks all scored.
Devonta Freeman ran nine times for 109 yards and a touchdown for the Seminoles (2-0) and James Wilder Jr. added 45 yards and a score. Karlos Williams may have been the most impressive of the bunch. The former safety, who moved to offense after the season opener, ran eight times for 110 yards and a score. His 65-yard run made it 31-7 early in the third quarter.
No. 14 OKLAHOMA 51, TULSA 20
NORMAN, Okla. -- Blake Bell passed for 413 yards and four touchdowns in his first start for Oklahoma.
Sterling Shepard caught eight passes for 123 yards and two touchdowns -- all career highs -- and Jaz Reynolds had 109 yards receiving and one score for Oklahoma (3-0). The Sooners scored on their first five possessions against Tulsa (1-2) to continue their dominance in the series, having won 12 of the last 13 games between the instate rivals.
The Sooners are 13-0 against Tulsa as a ranked team and 7-0 against the Golden Hurricane since Bob Stoops became Oklahoma's coach in 1999.
No. 16 UCLA 41, No. 23 NEBRASKA 21
LINCOLN, Neb. -- Brett Hundley threw three touchdown passes in the third quarter and UCLA came back from an 18-point deficit.
The Huskers (2-1), wearing alternate black jerseys instead of their traditional home red, looked to be in total control the first half. The Bruins (2-0) scored 35 straight points in 16 minutes. The barrage started with Paul Perkins' 10-yard touchdown run to cut Nebraska's lead to 21-10 the halftime.
Jordon James scored from 3 yards before Hundley threw TD passes of 28 yards to Shaquelle Evans, 12 yards to Phillip Ruhl and 3 yards to Nate Iese.
No. 19 WASHINGTON 34, ILLINOIS 24
CHICAGO -- Keith Price threw for 342 yards and two touchdowns, Bishop Sankey ran for a career-high 208 yards and No. 19 Washington beat Illinois 34-24 at Soldier Field on Saturday.
Josh Shirley added four sacks, and the Huskies came out on top after dropping seven of nine away from home. They hadn't won on the road outside the Pac-12 since beating Syracuse in 2007.
Washington (2-0) had a tougher time in this one after keeping high-powered Boise State without a touchdown in a 38-6 win two weeks ago.
INDIANA 42, BOWLING GREEN 10
BLOOMINGTON, Ind. -- Nate Sudfeld threw for 335 yards and two touchdowns and Cody Latimer had a career-high 137 yards receiving Saturday as Indiana pulled away in the second half for a 42-10 victory over Bowling Green.
Sudfeld's 33-yard touchdown pass to Latimer with 10:11 left in the third quarter stretched the lead to 18 and allowed the Hoosiers (2-1) to coast the rest of the way.
MINNESOTA 29, WESTERN ILLINOIS 12
MINNEAPOLIS -- David Cobb and Rodrick Williams each rushed for two touchdowns to lead Minnesota past Western Illinois 29-12 on Saturday afternoon.
Mitch Leidner finished 7 for 8 for 105 yards passing.
Trenton Norvell threw two touchdown passes without a turnover for the Leathernecks (2-1), the latest FCS foe in position for an upset at Minnesota. But Norvell finished 11 for 23 for 162 yards, and Western Illinois was outgained on the ground 213 yards rushing to 68. The Gophers forced eight punts.
MICHIGAN ST. 55, YOUNGSTOWN ST. 17
EAST LANSING, Mich. -- Connor Cook threw four touchdown passes in the first half, and the Michigan State offense finally looked smooth in a 55-17 victory over Youngstown State on Saturday.
Cook went 15 of 22 for 202 yards before being replaced by Tyler O'Connor early in the third quarter.
UCF 34, PENN ST. 31
PITTSBURGH -- Blake Bortles passed for 288 and three touchdowns and UCF stunned Penn State 34-31 on Saturday night.
Storm Johnson ran for a career-high 117 yards and a score and added a touchdown reception as the Knights (3-0) beat a Big Ten team for the first time in school history. UCF never trailed, having its way against Penn State's defense to give the newly minted American Athletic Conference a shot of respectability.
IOWA 27, IOWA ST. 21
IOWA CITY, Iowa -- Jake Rudock threw a pair of touchdown passes and ran for another score, Mark Weisman added 145 yards rushing and Iowa hung on to beat rival Iowa State 27-21 on Saturday night.
Kevonte Martin Manley had seven catches and a TD for the Hawkeyes (2-1). Iowa ran the ball 60 times for 218 yards and snapped a two-game losing streak against the Cyclones.
RUTGERS 28, EASTERN MICHIGAN 10
PISCATAWAY, N.J. -- Paul James ran for 192 yards and three touchdowns and Rutgers defeated Eastern Michigan 28-10 on Saturday when the Scarlet Knights honored the paralyzed Eric LeGrand by retiring his No. 52 jersey.
James made sure everyone went home happy, scoring on runs of 13, 55 and 52 yards as the Scarlet Knights (2-1) won their second straight and handed Eastern Michigan its second consecutive loss.
BUFFALO 26, STONY BROOK 23
BUFFALO, N.Y. -- Anthone Taylor scored on 6-yard touchdown run in the fifth overtime to give Buffalo a 26-23 win over Stony Brook on Saturday.
Taylor finished with 118 yards and two touchdowns on 24 carries, career highs, for the Seawolves (1-2).
NORTH TEXAS 34, BALL ST. 27
DENTON, Texas -- Derek Thompson threw for 274 yards and rushed 72 yards to lead North Texas to a 34-27 come-from-behind win over Ball State Saturday.
North Texas (1-1) struggled early as Ball State (2-1) sprinted to a 20-3 lead in the first quarter.
NORTHERN ILLINOIS 45, IDAHO 35
MOSCOW, Idaho -- Jordan Lynch threw for three touchdowns and ran for two more as heavily-favored Northern Illinois held off Idaho 45-35 on Saturday.
The Vandals (0-3), outscored 82-16 in their first two games, twice led the Huskies (2-0) by two touchdowns in the first half and tied the game at 35 in the opening minute of the fourth quarter on James Baker's second touchdown.